Excerpts from Books and Wikipedia
"Venice is defeated and the Ottoman Empire becomes master of the Aegean Sea." [Wikipedia: Timeline of Middle Ages] "In 1475 the Ottoman forces, under the command of Gedik Ahmet Pasha, conquered the Greek Principality of Theodoro and the Genoese colonies at Cembalo, Soldaia, and Caffa (modern Feodosiya). Thenceforth the khanate was a protectorate of the Ottoman Empire. The Ottoman sultan enjoyed veto power over the selection of new Crimean khans. The Empire annexed the Crimean coast but recognized the legitimacy of the khanate rule of the steppes, as the khans were descendants of Genghis Khan. In 1475, the Ottomans imprisoned Meñli I Giray for three years for resisting the invasion. After returning from captivity in Constantinople, he accepted the suzerainty of the Ottoman Empire. Nevertheless, Ottoman sultans treated the khans more as allies than subjects." [Wikipedia]