Excerpts from Books and Wikipedia
"A prodigious patron of the arts, he initiated the French Renaissance by attracting many Italian artists to work on the Château de Chambord, including Leonardo da Vinci, who brought the Mona Lisa with him, which Francis had acquired. Francis' reign saw important cultural changes with the rise of absolute monarchy in France, the spread of humanism and Protestantism, and the beginning of French exploration of the New World. Jacques Cartier and others claimed lands in the Americas for France and paved the way for the expansion of the first French colonial empire. . . . Following the policy of his predecessors, Francis continued the Italian Wars. The succession of Charles V to the Burgundian Netherlands, the throne of Spain, and his subsequent election as Holy Roman Emperor meant that France was geographically encircled by the Habsburg monarchy. In his struggle against Imperial hegemony, he sought the support of Henry VIII of England at the Field of the Cloth of Gold. When this was unsuccessful, he formed a Franco-Ottoman alliance with the Muslim sultan Suleiman the Magnificent, a controversial move for a Christian king at the time." [Wikipedia]